Dr. Anuradha Ramanathan received her M Sc. and Ph.D in biotechnology from IIT (Indian Institute of Technology), Mumbai. She has over 10 years drug discovery experience while at Aurigene Discovery Technologies Limited (a Dr Reddys Labs company) before joining Saksin Lifesciences. She has deep expertise in molecular biology, protein purification and in-vitro assay development for targets for oncology, inflammation and genetic disorders. As a team lead, Dr. Anuradha has had exposure to global drug discovery process from projects with collaborators from MNC pharmaceutical companies. Some of these projects successfully delivered preclinical candidates in oncology. She also has Research associate/trainee experience at premier academic institutes like TIFR and CCMB.
The department has expertise in process development for purification of monoclonal antibodies from microbial fermentation. The capabilities involve scale up process development from shake flask to fermentor level using affinity chromatography and other chromatographic steps for removal of process and product related impurities.
The infrastructure involves instruments like Akta Prime Plus, Akta Pure 150M, Tangential Flow Filtration and Sonicator.
DOWNSTREAM PROCESS DEVELOPMENT
Dr. Anuradha Ramanathan
Project Leader -
Downstream Process Development